Starvation induces free‐living Dictyostelium discoideum amoebae to form slugs that typically contain 100,000 cells. Only recently have sufficient clues become available to suggest how coordinated cell actions might result in slug movement. We propose a “squeeze‐pull” model that involves circumferential cells squeezing forward a cellular core, followed by pulling up of the rear. This model takes into account the different classes of cells in the slug; it is proposed that prestalk cells are engines and prespore cells are the cargo.

The effect of oxytocin on cognitive bias was investigated in rats in a modified conditioned place preference (CPP) paradigm. Fifteen male rats were trained to discriminate between two different cue combinations, one paired with palatable foods (reward training), and the other paired with unpalatable food (aversive training). Next, their reactions to two ambiguous cue combinations were evaluated and their latency to contact the goal pot recorded. Rats were injected with either oxytocin (OT) or saline with the prediction that rats administered (...) oxytocin would display a shorter average latency to approach on ambiguous trials. There was no significant difference between latencies to approach on ambiguous trials compared to reward trials, but the rats were significantly slower on the aversive compared to the ambiguous conditions. Oxytocin did not affect approach time; however, it was unclear, after follow-up testing, whether the OT doses tested were sufficient to produce the desired effects on cognitive bias. Future research should consider this possibility. (shrink)

Plato's views on the nature of the soul, by W.K.C. Guthrie.--Die Erneuerung der Philosophie in der Zeit Ciceros, von O. Gigon.--Gott und Seele im kaiserzeitlichen Denken, von W. Theiler.--Interprétations néo-platonisantes du livre VI de l'Énéide, par P. Courcelle.--Der Platonismus und die altchristliche Gedankenwelt, von J.H. Waszink.--Humanisme et christianisme chez Clément d'Alexandrie d'après le "Pédagogue," par H.I. Marrou.--Some aspects of Platonism in Islamic philosophy, by R. Walzer.

BackgroundStructured, systematic methods to formulate consensus recommendations, such as the Delphi process or nominal group technique, among others, provide the opportunity to harness the knowledge of experts to support clinical decision making in areas of uncertainty. They are widely used in biomedical research, in particular where disease characteristics or resource limitations mean that high-quality evidence generation is difficult. However, poor reporting of methods used to reach a consensus – for example, not clearly explaining the definition of consensus, or not stating (...) how consensus group panellists were selected – can potentially undermine confidence in this type of research and hinder reproducibility. Our objective is therefore to systematically develop a reporting guideline to help the biomedical research and clinical practice community describe the methods or techniques used to reach consensus in a complete, transparent, and consistent manner.MethodsThe ACCORD project will take place in five stages and follow the EQUATOR Network guidance for the development of reporting guidelines. In Stage 1, a multidisciplinary Steering Committee has been established to lead and coordinate the guideline development process. In Stage 2, a systematic literature review will identify evidence on the quality of the reporting of consensus methodology, to obtain potential items for a reporting checklist. In Stage 3, Delphi methodology will be used to reach consensus regarding the checklist items, first among the Steering Committee, and then among a broader Delphi panel comprising participants with a range of expertise, including patient representatives. In Stage 4, the reporting guideline will be finalised in a consensus meeting, along with the production of an Explanation and Elaboration document. In Stage 5, we plan to publish the reporting guideline and E&E document in open-access journals, supported by presentations at appropriate events. Dissemination of the reporting guideline, including a website linked to social media channels, is crucial for the document to be implemented in practice.DiscussionThe ACCORD reporting guideline will provide a set of minimum items that should be reported about methods used to achieve consensus, including approaches ranging from simple unstructured opinion gatherings to highly structured processes. (shrink)

Saint Anselm’s ontological argument for the existence of God, formulated nearly a millennium ago, continues to bedevil philosophers. There is no consensus about what, if anything, is wrong with it. Some philosophers insist that the argument is invalid. Others concede its validity but insist that it is unsound. A third group of philosophers maintain that Anselm begs the question. It has been argued, for example, that Anselm’s use of the name “God” in a premise assumes (or presupposes) precisely what has (...) to be proved, namely, that God exists. Another tack is to argue that the premise that God is possible implies or presupposes the conclusion that God exists, or perhaps that, in order to know that God is possible, one must know that God exists. Just as no consensus has emerged about what, if anything, is wrong with Anselm’s argument, no consensus has emerged about whether the argument begs the question. In this essay, I focus on the second type of claim made by the third group of philosophers—the claim that Anselm’s argument begs the question by assuming, as a premise, that God is possible. In particular, I focus on the argument of the contemporary analytic philosopher William Rowe, who has claimed, since at least 1975, that Anselm’s ontological argument begs the question. I argue that Rowe’s argument fails. (shrink)

Part I: The Life of Cognitive Science:. William Bechtel, Adele Abrahamsen, and George Graham. Part II: Areas of Study in Cognitive Science:. 1. Analogy: Dedre Gentner. 2. Animal Cognition: Herbert L. Roitblat. 3. Attention: A.H.C. Van Der Heijden. 4. Brain Mapping: Jennifer Mundale. 5. Cognitive Anthropology: Charles W. Nuckolls. 6. Cognitive and Linguistic Development: Adele Abrahamsen. 7. Conceptual Change: Nancy J. Nersessian. 8. Conceptual Organization: Douglas Medin and Sandra R. Waxman. 9. Consciousness: Owen Flanagan. 10. Decision Making: J. Frank Yates (...) and Paul A. Estin. 11. Emotions: Paul E. Griffiths. 12. Imagery and Spatial Representation: Rita E. Anderson. 13. Language Evolution and Neuromechanisms: Terrence W. Deacon. 14. Language Processing: Kathryn Bock and Susan M. Garnsey. 15. Linguistics Theory: D. Terence Langendoen. 16. Machine Learning: Paul Thagard. 17. Memory: Henry L. Roediger III and Lyn M. Goff. 18. Perception: Cees Van Leeuwen. 19. Perception: Color: Austen Clark. 20. Problem Solving: Kevin Dunbar. 21. Reasoning: Lance J. Rips. 22. Social Cognition: Alan J. Lambert and Alison L. Chasteen. 23. Unconscious Intelligence: Rhianon Allen and Arthur S. Reber. 24. Understanding Texts: Art Graesser and Pam Tipping. 25. Word Meaning: Barbara C. Malt. Part III: Methodologies of Cognitive Science:. 26. Artificial Intelligence: Ron Sun. 27. Behavioral Experimentation: Alexander Pollatsek and Keith Rayner. 28. Cognitive Ethology: Marc Bekoff. 29. Deficits and Pathologies: Christopher D. Frith. 30. Ethnomethodology: Barry Saferstein. 31. Functional Analysis: Brian Macwhinney. 32. Neuroimaging: Randy L. Buckner and Steven E. Petersen. 33. Protocal Analysis: K. Anders Ericsson. 34. Single Neuron Electrophysiology: B. E. Stein, M.T. Wallace, and T.R. Stanford. 35. Structural Analysis: Robert Frank. Part IV: Stances in Cognitive Science:. 36. Case-based Reasoning: David B. Leake. 37. Cognitive Linguistics: Michael Tomasello. 38. Connectionism, Artificial Life, and Dynamical Systems: Jeffrey L. Elman. 39. Embodied, Situated, and Distributed Cognition: Andy Clark. 40. Mediated Action: James V. Wertsch. 41. Neurobiological Modeling: P. Read Montague and Peter Dayan. 42. Production Systems: Christian D. Schunn and David Klahr. Part V: Controversies in Cognitive Science:. 43. The Binding Problem: Valerie Gray Hardcastle. 44. Heuristics and Satisficing: Robert C. Richardson. 45. Innate Knowledge: Barbara Landau. 46. Innateness and Emergentism: Elizabeth Bates, Jeffrey L. Elman, Mark H. Johnson, Annette Karmiloff-Smith, Domenico Parisi, and Kim Plunkett. 47. Intentionality: Gilbert Harman. 48. Levels of Explanation and Cognition Architectures: Robert N. McCauley. 49. Modularity: Irene Appelbaum. 50. Representation and Computation: Robert S. Stufflebeam. 51. Representations: Dorrit Billman. 52. Rules: Terence Horgan and John Tienson. 53. Stage Theories Refuted: Donald G. Mackay. Part VI: Cognitive Science in the Real World:. 54. Education: John T. Bruer. 55. Ethics: Mark L. Johnson. 56. Everyday Life Environments: Alex Kirlik. 57. Institutions and Economics: Douglass C. North. 58. Legal Reasoning: Edwina L. Rissland. 59. Mental Retardation: Norman W. Bray, Kevin D. Reilly, Lisa F. Huffman, Lisa A. Grupe, Mark F. Villa, Kathryn L. Fletcher, and Vivek Anumolu. 60. Science: William F. Brewer and Punyashloke Mishra. Selective Biographies of Major Contributors to Cognitive Science: William Bechtel and Tadeusz Zawidzki. (shrink)

Cognitive science is a cross-disciplinary enterprise devoted to understanding the nature of the mind. In recent years, investigators in philosophy, psychology, the neurosciences, artificial intelligence, and a host of other disciplines have come to appreciate how much they can learn from one another about the various dimensions of cognition. The result has been the emergence of one of the most exciting and fruitful areas of inter-disciplinary research in the history of science. This volume of original essays surveys foundational, theoretical, and (...) philosophical issues across the discipline, and introduces the foundations of cognitive science, the principal areas of research, and the major research programs. With a focus on broad philosophical themes rather than detailed technical issues, the volume will be valuable not only to cognitive scientists and philosophers of cognitive science, but also to those in other disciplines looking for an authoritative and up-to-date introduction to the field. (shrink)

In this paper, I analyze the notion of technique and a phenomenon, or practice, that I call the detachment of technique, or DT, for short. I argue that the technique of a significant human activity, such as thinking or teaching, is always embodied in persons and must be understood in relation to the context of ends that provides the technique whatever intellectual and moral authority it may have. With the use of two extended examples — one from Kurt Vonnegut's novel, (...) Player Piano, and the other from the critical commentary of Harry Broudy — I explore the consequences of detaching the formal or mechanical aspects of technique from its traditional context of ends. DT and expert systems, the most advanced form of DT, are shown to distort the technique and destroy the traditions of significant human activities. I also explore DT as a technique that is informed by the tradition of technological rationality. The most serious problem of DT is that when technique is detached from the traditions of significant human activities, it is also separated from the educational process whereby intelligence is developed. (shrink)

Artificial intelligence, or AI, is a cross-disciplinary approach to understanding, modeling, and creating intelligence of various forms. It is a critical branch of cognitive science, and its influence is increasingly being felt in other areas, including the humanities. AI applications are transforming the way we interact with each other and with our environment, and work in artificially modeling intelligence is offering new insights into the human mind and revealing new forms mentality can take. This volume of original essays presents the (...) state of the art in AI, surveying the foundations of the discipline, major theories of mental architecture, the principal areas of research, and extensions of AI such as artificial life. With a focus on theory rather than technical and applied issues, the volume will be valuable not only to people working in AI, but also to those in other disciplines wanting an authoritative and up-to-date introduction to the field. (shrink)

Sen’s Liberal paradox describes a conflict between weak Pareto, minimal liberalism, and either transitivity or a best element over a domain of individual preferences. This paper examines variants of that paradox with varying amounts of unconditional preferences. We define a notion of unconditional preferences under which, in the absence of Pareto, there can be no cycles. We then define a stronger condition, that makes an individual’s preferences for her own private attributes independent of all other attributes. Under this assumption, there (...) can be no cycles with or without Pareto. We also show there exists a social decision function satisfying those conditions. We then determine the probability of a cycle assuming a much weaker independence condition that does not restrict the domain. This probability converges to one as the number of non-private attributes within the social states increases. Finally, we use simulations to determine the probability that liberalism and Pareto conflict with best elements, maximal elements, and transitivity separately. (shrink)

In light of more contemporary interest in the concept of an immemorial past, this essay takes up the manner in which this idea figures in Merleau-Ponty’s works by turning to the famous reference to “a past that has never been present” in Phenomenology of Perception. In order to contextualize and think through what Merleau-Ponty means, I turn to a reference in the same text to “primary silence.” Merleau-Ponty’s concern is to disclose the differential between the concatenation of sensibility and expression (...) and what remains beyond the bounds of the sensible. The task of phenomenology, accordingly, is the disclosure of this primary silence, this primary non-sense. Finally, articulating that this differential never ceased to be a concern for Merleau-Ponty, and, turning to texts from the 1950s as well as to The Visible and the Invisible, we see the development of Merleau-Ponty’s thought as the consistent effort to think through this question. (shrink)

Analytic political philosophy tries to make our political language more precise. But in doing so it risks departing from our natural language and intuitions. This article examines this tension. We...

Florida International University, USA edwardj{at}fiu.edu ' + u + '@ ' + d + ' '/ /- -> Several authors have analyzed the optimal k -majority rule based on a variety of criteria. Buchanan and Tullock argued that, in constitutional settings, the criterion should be that all changes meet the Pareto criterion; otherwise the status quo should be preferred. They then asserted that unanimity rule would be the preferred voting rule in this setting. In parliamentary settings, they claimed that a (...) near majority rule would be preferred because it minimizes the sum of decision costs and external costs. This article investigates both claims in an N -voter, two-alternative setting. We show the conditions under which unanimity rule is less likely to select BT preferred alternatives than other k -majority rules and prove that the difference in performance can be negligible when N is large and certain weak conditions are met. Furthermore, if we define external costs as the expected number of losers from a BT-inferior vote, then external costs become negligible for a range of supermajority rules. This implies that unanimity rule and a range of supermajority rules should be equally preferred when decision costs are added. Finally, we show that the external cost function can actually increase for certain populations. Many of the broader conclusions should also hold for multiple alternatives. Key Words: constitutional design • Pareto criterion • external costs • social contract. (shrink)

This article addresses new approaches to the novel in the twenty-first century. It begins with an affirmation that even the most avant-garde of contemporary critics in the late twentieth and early twenty-first century share a commonality: a background in what was identified as “close reading” in the Anglo-American academic world and analyse de texte in French. After numerous declarations in recent decades about the death of the novel, the death of the author and the death of literary criticism, it is (...) evident that the novel as a genre has survived, authors remain a subject of study, and new approaches are possible. The study of trauma in fiction, as well as eco-criticism, are promising new points of departure. The required close reading implied by Twitter also opens up new possibilities. (shrink)

ABSTRACTIt is proposed that experts are able to integrate prior contextual knowledge with emergent visual information to make complex predictive judgments about the world around them, often under heightened levels of uncertainty and extreme time constraints. However, limited knowledge exists about the impact of anxiety on the use of such contextual priors when forming our decisions. We provide a novel insight into the combined impact of contextual priors and anxiety on anticipation in soccer. Altogether, 12 expert soccer players were required (...) to predict the actions of an oncoming opponent while viewing life-sized video simulations of 2-versus-2 defensive scenarios. Performance effectiveness and processing efficiency were measured under four conditions: no contextual priors about the action tendencies of the opponent and low anxiety ; no CP and high anxiety ; CP and LA; CP and HA. The provision of contextual priors did not affect processing efficiency, but it improved performance effectiveness... (shrink)

All volumes of Professor Guthrie's great history of Greek philosophy have won their due acclaim. The most striking merits of Guthrie's work are his mastery of a tremendous range of ancient literature and modern scholarship, his fairness and balance of judgement and the lucidity and precision of his English prose. He has achieved clarity and comprehensiveness.

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 RECORDER'S PREFACE . . . . . . . . . . . . . . . . . . (...) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 THE DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2.. (shrink)

Greek ways of thinking -- Matter and form: (ionians and pythagoreans) -- The problem of motion: (Heraclitus, Parmenides and the pluralists) -- The reaction towards humanism: (the Sophists and Socrates) -- Plato (I): the doctrine of ideas -- Plato (II): ethical and theological answers to the sophists -- Aristotle (I): the aristotelian universe -- Aristotle (II): human beings.